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Wound Management

Introduction and background

Authors: Christian Kaare Paaskesen Stud. Med, Magnus Balslev Avnstorp, MD,  Hasan G. Tekin MD.

In this chapter you will learn about the theory behind negative pressure wound therapy and products used in negative pressure wound therapy.


Negative Pressure Wound Therapy(NPWT) is the use of a wound dressing, sealed airtight and connected to a vacuum pump inducing controlled sub-atmospheric pressure (negative pressure).


NPWT have been used for centuries to promote wound healing. During the roman era, deep wound acquired during battle, was treated with “wound suctioning” by medical personal using their own mouth. This treatment was proven so succesfull, that it was considered indispensible to the roman army. In the 18th century, Anel, a french Surgeon, as inspired by this practice still used on the battlefield, Anel created syringe with a triangular tip to replace the mouth technique. Since then, other devices was developed, but it was in 1985 during the Soviet-Afghanistan war that Dr. Nail Bagaoudinov began using a negative pressure device in the combination with foam. Years later in the 1990’s, Drs. Louis Argenta and Michael Morykwas of Wake Forest University School of Medicine developed the technology we use today with polyurethane foam and mechanical suction.


  1. Miller C. The History of Negative Pressure Wound Therapy (NPWT): From “Lip Service” to the Modern Vacuum System. J Am Coll Clin Wound Spec. 2013;4(3):61-62. Published 2013 Nov 28. doi:10.1016/j.jccw.2013.11.002