Quiz – Oncologic Treatment (Case Based)

#1. A 62 year old woman is referred to you from her general practitioner due to a clinically suspicious mass in the left mamma. What is the name of the examination, that is used to diagnose carcinoma in the breast?

Cis-trans test

Pap smear test

Rubin's test

Shick's Test

Tripple Test

#2. A breast biopsy is needed to removes tissue from the suspicious mass. The tissue needs to examined under a microscope to be checked for the presence of breast cancer cells. Which type of biopsy is the most commonly used?

Fine needle aspiration cytology (FNAC)

Core needle biopsy (CNB)

Surgical biopsy

Excisional biopsy

Laparoscopic biopsy

#3. After the biopsy, you obtain this result. What do you suspect?

Ductal carcinoma in situ

Lobular carcinoma in situ

Invasive ductal carcinoma

Invasive lobular carcinoma

Inflammatory breast cancer

#4. Due to this patients family history, you suspect a possible mutation in a specific gene. Which one?

MET

BRAF

KRAS

ROS1

BRCA1/BRCA2

#5. If the patient has the mutation, what would be the recommended treatment in this specific case?

Treatment is watchful waiting since it is a slow-growing, non-aggressive breast cancer with clinical control scans every second year

Lumpectomy and postoperative radiotherapy

Mastectomy due to the known risk of BRCA1 or BRCA2 mutation

Treatment with an aromatase inhibitor (Letrozol) and a bisphosphonate

Chemotherapy only given in a series of three weeks

#6. During a routine check, you find a suspicious mass in a 50 year old woman. Which examination should you refer your patient to?

Mammography

X-ray

MRI

CT scan

Bone density scan (DEXA)

#7. After examination, you obtain the following result. What do you suspect?

Ductal carcinoma in situ

Lobular carcinoma in situ

Invasive ductal carcinoma

Invasive lobular carcinoma

Inflammatory breast cancer

#8. Studies show that LCIS frequently are bilateral (22-60%), but how often is it multicentered?

40%

50%

60%

70%

80%

#9. LCIS is considered a precursor for developing invasive lobular carcinoma later on. Which one of the following is of uttermost importance to register amongst other things to distinguish whether possible predictive factors exist?

Genetic predisposition and menopause

Smoking and drinking status

Kidney and liver function test

Comorbidities

Axillary lymph node status

#10. If a excisional biopsy shows LCIS, how often should the patient have control scans?

Every two months

Every six months

Every year

Every second year

It is not necessary with any control scans

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